| Chi tiết | Chemical Name: Polyethylene Glycol
Application: When attached to various protein medications, polyethylene glycol allows a slowed clearance of the carried protein from the blood. This makes for a longer-acting medicinal effect and reduces toxicity, and it allows longer dosing intervals. Examples include PEG-interferon alpha, which is used to treat hepatitis C, and PEGfilgrastim (Neulasta), which is used to treat neutropenia. It has been shown that polyethylene glycol can improve healing of spinal injuries in dogs.One of the earlier findings that polyethylene glycol can aid in nerve repair came from the University of Texas (Krause and Bittner).Polyethylene glycol is commonly used to fuse B-cells with myeloma cells in monoclonal antibody production.
PEG is used as an excipient in pharmaceutical products. Lower-molecular-weight variants are used as solvents in oral liquids and soft capsules, whereas solid variants are used as ointment bases, tablet binders, film coatings, and lubricants.
PEG is also used in lubricant eye drops.
It is the basis of many skin creams, as cetomacrogol, and sexual lubricants, frequently combined with glycerin.
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